By Richard LeComte
LEXINGTON, Ky. – Lift up a rock by a lake, and you may find planarians: complex, light-hating flatworms that prefer damp, dark hideouts. But what has Elizabeth Duncan so interested in them is their remarkable ability to reconstruct themselves when severed or injured.
“If we cut one of these worms into three pieces, each piece will create an entirely new worm,” said Duncan, assistant professor of biology in the University of Kentucky’s College of Arts & Sciences. “They regenerate a fairly complex body plan.”
That ability may lead Duncan and other researchers to fresh insights into biological regeneration. As a result, she recently earned a five-year, $250,000-a-year National Institute of General Medical Sciences Maximizing Investigators’ Research Award. The award will help her explore how specific enzyme activity affects stem cells’ ability